ESMO

Interviews and expert commentary from ESMO — study authors and key opinion leaders discuss the findings and their clinical implications.

Charles E Geyer MD; ESMO 2025: Antibody Drug Conjugate T-DXd Brings Longer Cancer-Free Survival for Patients with HER2-Positive Early Breast Cancer and Residual Invasive Disease
Audio Journal of Oncology

Charles E Geyer MD; ESMO 2025: Antibody Drug Conjugate T-DXd Brings Longer Cancer-Free Survival for Patients with HER2-Positive Early Breast Cancer and Residual Invasive Disease

Charles E Geyer MD, at ESMO 2025, discusses DESTINY-Breast05 results, revealing trastuzumab deruxtecan (T-DXd) significantly improves disease-free survival for HER2-positive early breast cancer patients with residual invasive disease after neoadjuvant therapy. T-DXd outperformed trastuzumab emtansin

20 March 2026
21:19
Li Zhang MD; ESMO 2025: Patients with EGFR-mutated Lung Cancer Progressing After Tyrosine Kinase Therapy Live Longer with Sacituzumab Tirumotecan Therapy
Audio Journal of Oncology

Li Zhang MD; ESMO 2025: Patients with EGFR-mutated Lung Cancer Progressing After Tyrosine Kinase Therapy Live Longer with Sacituzumab Tirumotecan Therapy

Antibody Drug Conjugate Prolongs Life in NSCLC refractory to EGFR TKI Therapy

19 November 2025
0:00
Xiuning Le MD PhD; ESMO 2025: Sevabertinib Success for Patients with HER2-Mutated Non-Small Cell Lung Cancer in SOHO-01 Study
Audio Journal of Oncology

Xiuning Le MD PhD; ESMO 2025: Sevabertinib Success for Patients with HER2-Mutated Non-Small Cell Lung Cancer in SOHO-01 Study

A new anti cancer drug sevabertinib, that targets mutated HER2, has proved effective in the SOHO-01 study among patients wiith HER2 mutated non small cell lung cancer. It has now been reported in the

31 October 2025
0:00
ESMO 2025; Christof Vulsteke MD PhD: Perioperative Enfortumab Vedotin Therapy With Pembrolizumab Boosts Event-Free and Overall Survival in Platinum-Ineligible Patients with Muscle-Invasive Bladder Cancer: KEYNOTE-905 study
Audio Journal of Oncology

ESMO 2025; Christof Vulsteke MD PhD: Perioperative Enfortumab Vedotin Therapy With Pembrolizumab Boosts Event-Free and Overall Survival in Platinum-Ineligible Patients with Muscle-Invasive Bladder Cancer: KEYNOTE-905 study

A big step forwards in the management of muscle invasive bladder cancer in which platinum cannot be used has been taken in the KEYNOTE-905 study of perioperative antibody drug conjugate thereapy with

30 October 2025
0:00
Xichun Hu MD PhD; ESMO 2025: Antibody Drug Conjugate Trastuzumab Botidotin Outperforms Trastuzumab Emtansine in Patients with HER2-Positive Unresectable or Metastatic Breast Cancer
Audio Journal of Oncology

Xichun Hu MD PhD; ESMO 2025: Antibody Drug Conjugate Trastuzumab Botidotin Outperforms Trastuzumab Emtansine in Patients with HER2-Positive Unresectable or Metastatic Breast Cancer

A Chinese ADC and a western ADC slugged it out at the 2025 ESMO held in Berlin.

28 October 2025
0:00
Martin Wermke MD; ESMO 2025: Initial Therapy with Bi-Specific T-cell Engager Tarlatamab Promises Better Outcomes in Patients with Small Cell Lung Cancer
Audio Journal of Oncology

Martin Wermke MD; ESMO 2025: Initial Therapy with Bi-Specific T-cell Engager Tarlatamab Promises Better Outcomes in Patients with Small Cell Lung Cancer

Tarlatamab, a bi-specific T-cell engager drug added to innitial immunochemotherapy brought encouraging initial survival outcomes in the DeLLphi-303 reported at the European Society for Medical Oncolog

27 October 2025
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John P. Crown MD MBA: ESMO 2025, Berlin: Adjuvant Ribociclib Brought Longer Freedom from Metastases for Patients with HR+/HER2- Early Breast Cancer: NATALEE Five Year Outcomes
Audio Journal of Oncology

John P. Crown MD MBA: ESMO 2025, Berlin: Adjuvant Ribociclib Brought Longer Freedom from Metastases for Patients with HR+/HER2- Early Breast Cancer: NATALEE Five Year Outcomes

John P. Crown MD MBA: ESMO 2025, Berlin: Adjuvant Ribociclib Brought Longer Freedom from Metastases for Patients with HR+/HER2- Early Breast Cancer: NATALEE Five Year Outcomes

24 October 2025
0:00
Javier C Cortés MD PhD: ESMO 2025, Berlin: Initial Therapy with Sacituzumab Govitecan Improves Progression-Free Survival in Patients with Newly-Diagnosed Metastatic Triple Negative Breast Cancer—ASCENT-03 study
Audio Journal of Oncology

Javier C Cortés MD PhD: ESMO 2025, Berlin: Initial Therapy with Sacituzumab Govitecan Improves Progression-Free Survival in Patients with Newly-Diagnosed Metastatic Triple Negative Breast Cancer—ASCENT-03 study

Javier Cortés tells his findings from ASCENT-03 as reported to ESMO 2025 in Berlin with antibody drug conjugate as initial therapy for TNBC in patients testing negative for PD-1/PD-L1

23 October 2025
0:00
Which New Combination for Metastatic Renal Cell Cancer?
Audio Journal of Oncology

Which New Combination for Metastatic Renal Cell Cancer?

MUNICH—A leading European oncologist acknowledged the impressive life-extending potential of new drug combinations for metastatic renal cell carcinoma discussed at the 2018 annual congress of the Euro

12 November 2018
9 minutes
Two Drug Combination Doubled Kidney Cancer Progression Free Survival
Audio Journal of Oncology

Two Drug Combination Doubled Kidney Cancer Progression Free Survival

MUNICH— A doubling of progression free survival (PFS) and objective response rate (ORR) was observed in patients who had their previously untreated advanced renal cell cancer (RCC) treated with a comb

7 November 2018
9 minutes
ALK—Targeted Lung Cancer Drugs Benefited Real World Patients 
Audio Journal of Oncology

ALK—Targeted Lung Cancer Drugs Benefited Real World Patients 

MUNICH— Anaplastic lymphoma kinase (ALK) inhibitors are as effective in “real world” clinical use for treating patients with non-small cell lung cancer (NSCLC) who test positive for ALK ge

7 November 2018
9 minutes
First Line PARP Inhibition For Ovarian Cancer Assessed
Audio Journal of Oncology

First Line PARP Inhibition For Ovarian Cancer Assessed

MUNICH—The role of poly ADP ribose polymerase (PARP) inhibitors for treating newly diagnosed advanced ovarian cancer was under review at the 2018 annual congress of the European Society for Medical On

2 November 2018
7 Minutes
BRCA1/2 Ovarian Cancer—Three Years Disease Free with First-Line Olaparib
Audio Journal of Oncology

BRCA1/2 Ovarian Cancer—Three Years Disease Free with First-Line Olaparib

BRCA1/2 Ovarian Cancer—Three Years Disease Free with First-Line Olaparib MUNICH—An “unprecedented improvement” in progression free survival (PFS) was observed in the randomized controlled

1 November 2018
8 mins
PD-L1 Immunotherapy Delayed Triple Negative Breast Cancer Progression
Audio Journal of Oncology

PD-L1 Immunotherapy Delayed Triple Negative Breast Cancer Progression

MUNICH— Immunotherapy with the anti programmed death ligand 1 (PD-L1) checkpoint inhibitor atezolizumab in combination with nab-paclitaxel chemotherapy prolonged progression-free survival (PFS) among

31 October 2018
6 mins
Genomically Targeted Therapy Delays Advanced Breast Cancer Progression
Audio Journal of Oncology

Genomically Targeted Therapy Delays Advanced Breast Cancer Progression

MUNICH—A combination of the phosphoinositide 3-kinase (PI3K) inhibitor alpelisib plus fulvestrant significantly extended progression free survival (PFS) compared to placebo plus fulvestr

31 October 2018
6 m ins
Palbociclib Combination Prolongs Life After Breast Cancer Hormone Therapy
Audio Journal of Oncology

Palbociclib Combination Prolongs Life After Breast Cancer Hormone Therapy

MUNICH—Patients with hormone receptor-positive (HR+) human epidermal growth factor receptor 2-negative (HER2−) advanced breast cancer who were treated with a combination of the cyclin dependent kina

29 October 2018
7 minutes
Long Overall Survival in Ceritinib-Treated ALK-Positive Lung Cancer
Audio Journal of Oncology

Long Overall Survival in Ceritinib-Treated ALK-Positive Lung Cancer

MUNICH—More than four years median overall survival was reported in patients treated with an inhibitor of anaplastic lymphoma kinase (ALK) for their ALK gene rearranged non-small cell lung cancer (NSC

27 October 2018
7 minutes
Cabozantinib Improved Hepatocellular Carcinoma Survival Beyond Sorafenib
Audio Journal of Oncology

Cabozantinib Improved Hepatocellular Carcinoma Survival Beyond Sorafenib

BARCELONA—Oral cabozantinib “significantly improved” overall survival (OS) and progression free survival (PFS) compared to placebo in patients with advanced hepatocellular carcinoma(HCC) w

15 October 2018
8 mins
First-Line Pembrolizumab Boosts Survival in PD-L1-Positive Advanced Lung Cancer
Audio Journal of Oncology

First-Line Pembrolizumab Boosts Survival in PD-L1-Positive Advanced Lung Cancer

Audio Journal of Oncology, January 2, 2017 COPENHAGEN—Patients with metastatic non-small cell lung cancers (NSCLC) expressing the programmed cell-death ligand 1 (PD-L1) protein responded better to ini

2 January 2017
11:00
Second-Generation ALK Inhibitor = Longer PFS in ALK+ Lung Cancer After Crizotinib
Audio Journal of Oncology

Second-Generation ALK Inhibitor = Longer PFS in ALK+ Lung Cancer After Crizotinib

COPENHAGEN—Longer progression free survival (PFS) was achieved in patients with ALK-rearranged non-small cell lung cancer (NSCLC) previously treated with crizotinib randomised to treatment with the se

8 December 2016
8:52 secs
PD-L1 Checkpoint Inhibitor Immunotherapy Boosts Survival in Lung Cancer
Audio Journal of Oncology

PD-L1 Checkpoint Inhibitor Immunotherapy Boosts Survival in Lung Cancer

The Audio Journal of Oncology Reporting from the 2016 Congress of the European Society of Medical Oncology COPENHAGEN—The anti-PD-L1 (programmed cell death ligand-1) immunotherapy agent atezolizumab e

6 December 2016
10:30 secs
Lung Cancer—First-Line Checkpoint Inhibitor Combination Benefit
Audio Journal of Oncology

Lung Cancer—First-Line Checkpoint Inhibitor Combination Benefit

COPENAGEN—Adding the PD-1 (programmed cell death protein 1) antibody pembrolizumab to standard first-line chemotherapy with carboplatin and pemetrexed for previously-untreated patients with advanced n

23 November 2016
11:00 mins
Early Lung Cancer Responds to Preoperative Nivolumab
Audio Journal of Oncology

Early Lung Cancer Responds to Preoperative Nivolumab

COPENHAGEN—In a phase I study reported at the 2016 congress of the European Society for Medical Oncology (ESMO) six out of 15 patients with resectable early non-small cell lung cancer had “major

17 November 2016
9:00
Vantictumab Combination Benefits Patients with Stage IV Pancreatic Cancer
Audio Journal of Oncology

Vantictumab Combination Benefits Patients with Stage IV Pancreatic Cancer

Audio Journal of Oncology COPENHAGEN, Denmark—In a phase 1b study patients with previously untreated stage IV pancreatic cancer responded or derived “clinical benefit” from a regimen in wh

31 October 2016
9:00 mins
Niraparib Quadruples Progression Free Survival in Platinum-Sensitive Ovarian Cancer
Audio Journal of Oncology

Niraparib Quadruples Progression Free Survival in Platinum-Sensitive Ovarian Cancer

COPENHAGEN, Denmark—Marked prolongation of progression free survival (PFS) in all groups of patients with platinum-sensitive recurrent ovarian cancer was reported at the European Society for Medical O

21 October 2016
7:00
Cyclin-Dependent Kinase Inhibition Overcomes Endocrine Resistance in Advanced Breast Cancer
Audio Journal of Oncology

Cyclin-Dependent Kinase Inhibition Overcomes Endocrine Resistance in Advanced Breast Cancer

DESCRIPTION COPENHAGEN, Denmark—The efficacy of endocrine therapy in breast cancer was improved—in the MONALEESA-2 study—by the addition of the cyclin-dependent kinase (CDK) 4/6 inhibitor ribociclib t

14 October 2016
10:48 secs
Adjuvant Checkpoint Inhibition Extends Disease-Free and Overall Survival in Patients with Stage III Melanoma
Audio Journal of Oncology

Adjuvant Checkpoint Inhibition Extends Disease-Free and Overall Survival in Patients with Stage III Melanoma

COPENHAGEN, Denmark—Checkpoint inhibition prolonged life when used as adjuvant therapy among patients with fully resected stage III malignant melanoma in the EORTC 18071 randomized phase III compariso

13 October 2016
6:30
Audio Journal of Oncology in Advance – November 1st, 2006
Audio Journal of Oncology

Audio Journal of Oncology in Advance – November 1st, 2006

David Cameron Martine Piccart Eric Van Cutsem Jim Cassidy Volker Heinemann Lapatinib Better for Patients with HER2+ Refractory Breast Cancer Pre-treated with Chemotherapy and Trastuzumab REFERENCE: ES

1 November 2006
0:00
Audio Journal of Oncology Breast Cancer Special 2005
Audio Journal of Oncology

Audio Journal of Oncology Breast Cancer Special 2005

Reporting from: – San Antonio Breast Cancer Symposium, December 8-11, 2004 – European Society for Medical Oncology Congress, October 29-November 10, 2004, Vienna In this edition: Raimund J

8 January 2006
0:00
Audio Journal of Oncology 13.2, February 2005
Audio Journal of Oncology

Audio Journal of Oncology 13.2, February 2005

Reporting from: – Annual Meeting of the American Society of Hematology, December 4-7, 2004, San Diego – Chemotherapy Foundation Symposium, November 10-13 2004, New York – European So

8 February 2005
0:00
Audio Journal of Oncology 13.1, January 2005
Audio Journal of Oncology

Audio Journal of Oncology 13.1, January 2005

Reporting from: – European Society for Medical Oncology Congress, October 29-November 10, 2004, Vienna – Journal of Clinical Oncology – New England Journal of Medicine – Lancet

8 January 2005
0:00