ESMO 2016
European Society for Medical Oncology Congress
Interviews and expert commentary from ESMO 2016 — study authors and key opinion leaders discuss the findings and their clinical implications.


First-Line Pembrolizumab Boosts Survival in PD-L1-Positive Advanced Lung Cancer
Audio Journal of Oncology, January 2, 2017 COPENHAGEN—Patients with metastatic non-small cell lung cancers (NSCLC) expressing the programmed cell-death ligand 1 (PD-L1) protein responded better to ini

Second-Generation ALK Inhibitor = Longer PFS in ALK+ Lung Cancer After Crizotinib
COPENHAGEN—Longer progression free survival (PFS) was achieved in patients with ALK-rearranged non-small cell lung cancer (NSCLC) previously treated with crizotinib randomised to treatment with the se

PD-L1 Checkpoint Inhibitor Immunotherapy Boosts Survival in Lung Cancer
The Audio Journal of Oncology Reporting from the 2016 Congress of the European Society of Medical Oncology COPENHAGEN—The anti-PD-L1 (programmed cell death ligand-1) immunotherapy agent atezolizumab e

Lung Cancer—First-Line Checkpoint Inhibitor Combination Benefit
COPENAGEN—Adding the PD-1 (programmed cell death protein 1) antibody pembrolizumab to standard first-line chemotherapy with carboplatin and pemetrexed for previously-untreated patients with advanced n

Early Lung Cancer Responds to Preoperative Nivolumab
COPENHAGEN—In a phase I study reported at the 2016 congress of the European Society for Medical Oncology (ESMO) six out of 15 patients with resectable early non-small cell lung cancer had “major

Vantictumab Combination Benefits Patients with Stage IV Pancreatic Cancer
Audio Journal of Oncology COPENHAGEN, Denmark—In a phase 1b study patients with previously untreated stage IV pancreatic cancer responded or derived “clinical benefit” from a regimen in wh

Niraparib Quadruples Progression Free Survival in Platinum-Sensitive Ovarian Cancer
COPENHAGEN, Denmark—Marked prolongation of progression free survival (PFS) in all groups of patients with platinum-sensitive recurrent ovarian cancer was reported at the European Society for Medical O

Cyclin-Dependent Kinase Inhibition Overcomes Endocrine Resistance in Advanced Breast Cancer
DESCRIPTION COPENHAGEN, Denmark—The efficacy of endocrine therapy in breast cancer was improved—in the MONALEESA-2 study—by the addition of the cyclin-dependent kinase (CDK) 4/6 inhibitor ribociclib t

Adjuvant Checkpoint Inhibition Extends Disease-Free and Overall Survival in Patients with Stage III Melanoma
COPENHAGEN, Denmark—Checkpoint inhibition prolonged life when used as adjuvant therapy among patients with fully resected stage III malignant melanoma in the EORTC 18071 randomized phase III compariso