cancer
Interviews and expert commentary tagged “cancer” — the latest oncology research and clinical practice from the Audio Journal of Oncology.

Hassan Mohammed Abushukair MD; AACR 2026: Immune Checkpoint Inhibitor-Induced Myocarditis within One Month Predicts Lethal “Triple M Overlap Syndrome”
Immune Checkpoint Inhibitor-Induced Myocarditis within One Month Predicts Lethal “Triple M Overlap Syndrome” An interview with: Hassan Mohammed Abushukair MD, Post-Doctoral Researcher, Oklahoma Univer

Aditya Bardia MD MPH; 2025 San Antonio Breast Cancer Symposium: Selective Estrogen Degrader Giredestrant Improves on Standard Endocrine Therapy for Patients with ER-positive, HER2-negative Early Breast Cancer: Phase III lidERA Breast Cancer trial Findings
A seective estrogen degrader out-performed AI’s in ER+ HER- early breast cancer

Li Zhang MD; ESMO 2025: Patients with EGFR-mutated Lung Cancer Progressing After Tyrosine Kinase Therapy Live Longer with Sacituzumab Tirumotecan Therapy
Antibody Drug Conjugate Prolongs Life in NSCLC refractory to EGFR TKI Therapy

ESMO 2025; Christof Vulsteke MD PhD: Perioperative Enfortumab Vedotin Therapy With Pembrolizumab Boosts Event-Free and Overall Survival in Platinum-Ineligible Patients with Muscle-Invasive Bladder Cancer: KEYNOTE-905 study
A big step forwards in the management of muscle invasive bladder cancer in which platinum cannot be used has been taken in the KEYNOTE-905 study of perioperative antibody drug conjugate thereapy with

Rebecca Dent MD: ESMO Previous Highlights: Neo-Adjuvant Therapy for Triple Negative Breast Cancer, Checkpoint Inhibition, AI, Cancer Vaccines, and More ……
Rebecca Dent surveys the most recent ESMO Annual Meeting to prepare our thoughts for the ESMO 2025 meeting

Bart Neyns MD PhD: Patients with Recurrent Glioblastoma Lived Markedly Longer in Phase 1 Study of Intracranial Autologous Myeloid Dendritic Cell Therapy
bart-neyns-md-phd-injectng-cells-into-cranial-cavity-for-recurrent-glioblastoma-long-survival

Stacey Kenfield ScD and June Chan ScD: Prostate Cancer Management: New Evidence of Big Benefit from Exercise:
Stacey Kenfield and June Chan UCSF

Jonathan T. Yang MD PhD: Radiosensitizer Shows Early Clinical Promise to Support Glioblastoma Radiotherapy
Jonathan T Yang, MD, PhD

Adjuvant Nivolumab Extends Disease-Free Survival in Patients with High-Risk Head and Neck Cancers
“Adjuvant nivolumab added to chemoradiotherapy after surgery provided a statistically and clinically meaningful disease-free survival improvement in PD-L1 all-comers patients. This is the first time i

Single-cell RNA Sequencing Provides Comprehensive Map of Acute Myeloid Leukemia Cell States
Andy Zeng, Toronto: Transcriptome Map Key to Malignant Transformation in AML

Orteronel shows no survival advantage in metastatic castration-resistant prostate cancer: phase III randomized study finds
SAN FRANCISCO—Orteronel — a non-steroidal selective inhibitor of 17,20-lyase — did not achieve a significant improvement in overall survival in 1099 patients randomised to treatment with this “a

Idelalisib: new targeted therapy improves outlook for patients with chronic lymphocytic leukaemia
NEW ORLEANS—A new oral tyrosine kinase inhibitor drug — idelalisib — has proved effective — and to have low toxicity — in patients with chronic lymphocytic leukaemia (CLL). Richard Furman MD from Weil

First effective treatment for “orphan disease’: Anti I/L 6 antibody brings remissions in Multicentric Castleman’s Disease
The rare, fatal lympho-proliferative condition: Multicentric Castleman’s Disease — MCD — could soon be treatable following findings announced at the American Society of Hematology annual meeting

Chimeric antigen receptor T-cell therapy: high remission rate in relapsed, refractory acute lymphoblastic leukemia
NEW ORLEANS—High remission rates with extended survival are being achieved in patients who had failed all other therapies — including allogeneic stem cell transplantation — for their acute lymphoblast

Healthcare Delivery And Spending: Big Impact On Cancer Survival
LONDON—Inequalities in cancer care delivery and overall spending have had a big impact on cancer survival rates in Europe, according to Michel Coleman, Professor of Epidemiology and Vital Statistics a

Global Handwashing Day!; Sex and Health; More Prisoners: More TB; How to Survive Cancer
Val Curtis Global Handwashing Day is October 15th, 2008: an opportunity to remind everybody that millions of lives, especially children’s lives, can be saved by avoiding diarrhoea and other dise

Audio Journal of Oncology Volume 16 Number 11
Scientific Editors: George Canellos (Boston), Pat Price (Manchester), Gianni Bonadonna (Milan), Gordon McVie (Milan) Sarah Maxwell and Peter Goodwin report from: American Society of Clinical Oncology

Audio Journal of Oncology Volume 16 Number 10
Scientific Editors: George Canellos (Boston), Pat Price (Manchester), Gianni Bonadonna (Milan), Gordon McVie (Milan) Commenting Expert: Michael Untch, HELIOS Klinikum, Berlin In this edition Peter Goo

Audio Journal of Oncology Volume 16 Number 9
Scientific Editors: George Canellos (Boston), Pat Price (Manchester), Gianni Bonadonna (Milan), Gordon McVie (Milan) Commenting Expert: Emiel Rutgers, Netherlands Cancer Institute, Amsterdam Angel Rod

Audio Journal of Oncology Volume 16 Number 8
Scientific Editors: George Canellos, Pat Price, Gordon McVie, Gianni Bonadonna In this edition: Bevacizumab and Survival in Metastatic Breast Cancer Source: N Engl J Med 357:26 George Canellos, Dana-F

Risks From Stopping Cancer Trials Early!
Giovanni Apolone In this edition of Audio News, presented by Peter Goodwin, Giovanni Apolone (Mario Negri Institute, Milan) and Stuart Pocock (London School of Hygiene and Tropical Medicine), talk abo

Debate: Adjuvant Chemotherapy Should Be Standard in Stage I Non-Small Cell Lung Cancer
Giorgio Scagliotti Robert Pirker GIORGIO SCAGLIOTTI, University of Turin ROBERT PIRKER, Medical University of Vienna A heated debate took place at the European Congress on Lung Cancer in Turin between

Front Line Therapy in Non-Small Cell Lung Cancer
Nick Thatcher NICK THATCHER, Christie Hospital, Manchester There is a proven benefit in survival if you give your patients cis-platinum based chemotherapy after resection for non-small cell lung cance

New Targets Bring Promise For Lung Cancer Therapy
Egbert Smit EGBERT SMIT, Free University of Amsterdam There are a number of promising new molecular targets for lung cancer chemotherapy which were discussed at the Turin congress by Egbert Smit. He t

Target Angiogenesis for Lung Cancer With Multiple Tyrosine Kinase Inhibitors
Silvia Novello SILVIA NOVELLO, University of Turin Future improvements in drug treatment of lung cancer may be made by inhibiting more than one tyrosine kinase simultaneously. So said Silvia Novello w

Bevacizumab: New Standard for Non-Small Cell Lung Cancer?
Christian Manegold Nick Thatcher Christian Manegold, Heidelberg University Medical Center, Manheim Nick Thatcher, Christie Hospital, Manchester Is bevacizumab a new standard of care for patients with

Audio Journal of Oncology in Advance – March 15th, 2008
Volume 16 Number 6 (March 15th, 2008) reporting from: 4th European Congress on Hematologic Malignancies (February 22-24, 2008, Paris) American Society of Hematology Annual Meeting (December 8-11, 2007

Multiple Myeloma: Towards A Chronic Disease With Cure On The Horizon
Kenneth Anderson Reporting From: 4th European Congress on Hematologic Malignancies, Paris 22-24 February, 2008 KENNETH ANDERSON, Dana-Farber Cancer Institute, Boston Multiple myeloma may soon be consi

Oral Capecitabine: As Good As Fluorouracil Second Line for Metastatic Colorectal Cancer
David Cunningham REFERENCE: Abstract 3012, ECCO 14, The European Cancer Conference, Barcelona, 23 – 27 September 2007 DAVID CUNNINGHAM, Royal Marsden Hospital, London The oral agent capeticabine

Hormone Refractory Prostate Cancer: Increased Progression-Free Survival With Satraplatin and Prednisone
Cora Sternberg REFERENCE: Abstract 4010, ECCO 14, The European Cancer Conference, Barcelona, 23 – 27 September 2007 CORA STERNBERG, San Camillo and Forlanini Hospital, Rome Satraplatin could pro

Gastrointestinal Cancers: Progress with Targeted Therapies
Robert Mayer ROBERT MAYER, Dana-Farber Cancer Institute, Boston One of the leading participants at the 2008 Gastrointestinal Cancers Symposium, Robert Mayer, gave Peter Goodwin his assessment of some

Adjuvant Chemoradiotherapy: Big Gains In Pancreas Cancer
Charles Hsu CHARLES HSU, Johns Hopkins University, Baltimore Big improvements in overall survival were achieved by combining radiation with adjuvant chemotherapy for patients with pancreas cancer in a

ATAC Trial: Anastrozole Still Superior At Over Eight Years’ Follow Up
Jack Cuzick JACK CUZICK, Wolfson Institute of Preventive Medicine, London New data from the ATAC trial, which is testing anastrozole and tamoxifen in early breast cancer, have demonstrated the continu

New Drug RAD001 Plus Letrozole In Neoadjuvant Therapy For Breast Cancer
Jose Baselga JOSE BASELGA, Vall d’Hebron Hospital, Barcelona RAD001, a drug targeted at the mTor pathway, has been combined with letrozole in a randomised phase II trial in breast cancer. The in

Live Report from ASH:<br />Oblimersen Extends Survival in Chronic Lymphocytic Leukemia
Susan O’Brien SUSAN O’BRIEN, MD Anderson Cancer Center, Houston For patients with relapsed or refractory CLL, oblimersen extends survival when added to standard fludarabine/cyclophosphamid

Live Report from ASH:<br />Dasatinib Effective At Two Years’ Follow Up in Chronic Phase CML
Richard Stone RICHARD STONE, Dana-Farber Cancer Institute, Boston GEORGE CANELLOS, Dana-Farber Cancer Institute New data shows that dasatinib is giving durable responses in patients with chronic phase

Live Report from ASH:<br />Interleukin-2 For Acute Myeloid Leukemia In First Remission?
Jonathan Kolitz JONATHAN KOLITZ, Monter Cancer Center, Lake Success, NY GEORGE CANELLOS, Dana-Farber Cancer Institute For patients with acute myeloid leukemia in first remission, new data suggests tha

Two New Second-Line Options For Patients With Advanced or Metastatic Non-Small Cell Lung Cancer
Jean-Yves Douillard Gordon McVie REFERENCE: Abstracts: 6507 & 2LB, ECCO 14, The European Cancer Conference, Barcelona, 23 – 27 September 2007 JEAN-YVES DOUILLARD, Centre René Gauducheau, N

Endothelin Antagonist Keeps Patients with Hormone Refractory Prostate Cancer Alive Longer
Nicholas James Gordon McVie REFERENCE: Abstract: 3LB (Presidential Session), ECCO 14, The European Cancer Conference, Barcelona, 23 – 27 September 2007 NICHOLAS JAMES, Birmingham University COMM

Neoadjuvant Trastuzumab: Marked Benefit in HER2-Positive Inflammatory Breast Cancer
Jose Baselga Gordon McVie REFERENCE: ABSTRACT 2030, ECCO 14, The European Cancer Conference, Barcelona, 23 – 27 September 2007 JOSE BASELGA, Vall d’Hebron University Hospital, Barcelona CO

Laparoscopic-Assisted Resection for Colorectal Cancer
Pierre Guillou David Jayne REFERENCE: J Clin Oncol 25:3061-3068 PIERRE GUILLOU, St James’ Hospital, Leeds COMMENT: DAVID JAYNE, St James’ Hospital, Leeds Laparoscopic-assisted resection fo

KRAS Mutation: Powerful Molecular Predictor of Cetuximab Response in Patients With Metastatic Colorectal Cancer
Pierre Laurent-Puig Bill Hait REFERENCE: ABSTRACT: 5671, American Association for Cancer Research, April 14-18, 2007, Los Angeles PIERRE LAURENT-PUIG, Hôpital Européen Georges Pompidou, Paris COMMEN

Virus Plus Cytokine Fight Primary and Metastatic Cancer
Paul Fisher REFERENCE: Meet the Professor Session, AACR 2007, Los Angeles PAUL FISHER, Columbia University, New York Patients with cancer could soon be treated with adenoviruses capable of infecting b

Audio Journal of Oncology in Advance – May 15th, 2007 – reporting from: American Association for Cancer Research, April 14-18, 2007, Los Angeles, CA
Alberto Sobrero Cetuximab With Irinotecan: Phase III Study Shows Benefit in Patients with Oxaliplatin-Refractory Colorectal Cancer REFERENCE: ABSTRACT LB-2; AACR 2007, Los Angeles, Plenary Session ALB

Audio Journal of Oncology in Advance – March 1st, 2007
Lorie Hughes Rachel Ellsworth Rowan Chlebowski Victor Vogel Local Excision Alone for Selected Patients with Ductal Carcinoma In Situ? REFERENCE: Abstract: 29 LORIE HUGHES, The Hope Center, Cartersvill

Audio Journal of Oncology in Advance – January 15th, 2007 – HERA Study Results Confirm Trastuzumab Benefit in HER2 Positive Early Breast Cancer
IAN SMITH, Royal Marsden Hospital, London REFERENCE: Lancet 369:29 Confirmation of the life-extending benefits of trastuzumab adjuvant therapy for early breast cancer has been published recently in th

Audio Journal of Oncology in Advance – January 1st, 2007 – Reporting from San Antonio Breast Cancer Symposium, December 14-17, 2006
Dennis Slamon George Peoples James Holland Massimo Christofanilli Trastuzumab: Mature Results in Early Breast Cancer Show Superiority REFERENCE: San Antonio Breast Cancer Symposium 2006, Abstract: 52

Audio Journal of Oncology in Advance – December 1st, 2006
Clifford Hudis Mark Einstein Tony Greco James Berenson Edward Ambinder Breast Cancer: HER2 Still a Useful Target After Trastuzumab Resistance REFERENCE: Chemotherapy Foundation Symposium XXIV 8-11 Nov

ASCO Audio Journal of Oncology – September 15th, 2006
Robert Ozols William See Ruth Lupu Improving on Standard Treatment in Ovarian Cancer: Have We Hit a Wall? REFERENCE: Abstract 5002, 2006 ASCO Annual Meeting; N Engl J Med 2006, 354:34-43 ROBERT OZOLS,