patient
Interviews and expert commentary tagged “patient” — the latest oncology research and clinical practice from the Audio Journal of Oncology.

Routine Angioplasty Recommended After Thrombolysis
Warren Cantor Tony Gershlick REFERENCE: Abstract 2404-3 SCAI-ACCi2 Late-Breaking Clinical Trials II: Acute Myocardial Infarction Warren Cantor, University of Toronto COMMENT: Tony Gershlick, Leicester

Debate: Adjuvant Chemotherapy Should Be Standard in Stage I Non-Small Cell Lung Cancer
Giorgio Scagliotti Robert Pirker GIORGIO SCAGLIOTTI, University of Turin ROBERT PIRKER, Medical University of Vienna A heated debate took place at the European Congress on Lung Cancer in Turin between

Front Line Therapy in Non-Small Cell Lung Cancer
Nick Thatcher NICK THATCHER, Christie Hospital, Manchester There is a proven benefit in survival if you give your patients cis-platinum based chemotherapy after resection for non-small cell lung cance

Bevacizumab: New Standard for Non-Small Cell Lung Cancer?
Christian Manegold Nick Thatcher Christian Manegold, Heidelberg University Medical Center, Manheim Nick Thatcher, Christie Hospital, Manchester Is bevacizumab a new standard of care for patients with

“Total Therapy” Possible Cure For Multiple Myeloma?
Bart Barlogie Reporting From: 4th European Congress on Hematologic Malignancies, Paris 22-24 February, 2008 BART BARLOGIE, University of Arkansas, Little Rock A treatment known as “total therapy

London School of Hygiene & Tropical Medicine Audio News – Europe’s Surge Against Cancer
Michel Coleman Michel Coleman (London School of Hygiene and Tropical Medicine) explains how cancer will become a new priority in the EU.

Hormone Refractory Prostate Cancer: Increased Progression-Free Survival With Satraplatin and Prednisone
Cora Sternberg REFERENCE: Abstract 4010, ECCO 14, The European Cancer Conference, Barcelona, 23 – 27 September 2007 CORA STERNBERG, San Camillo and Forlanini Hospital, Rome Satraplatin could pro

Adjuvant Chemoradiotherapy: Big Gains In Pancreas Cancer
Charles Hsu CHARLES HSU, Johns Hopkins University, Baltimore Big improvements in overall survival were achieved by combining radiation with adjuvant chemotherapy for patients with pancreas cancer in a

Meta-Analysis Proves Statins Help Patients With Diabetes
Colin Baigent REFERENCE: Lancet 371:117 January 11, 2008 COLIN BAIGENT, Oxford University Statins were found to cut cardiovascular event rates by a fifth among patients with both Type I and Type II di

Non Drug Intervention: Better Than Antipsychotic Drugs for Aggressive Challenging Behaviour in Intellectual Disability
Peter Tyrer REFERENCE: Lancet 371:57 January 5, 2008 PETER TYRER, Imperial College, W6 8RP London A randomized study comparing treatment with risperidone, or haloperidol, or placebo to treat patients

Live Report from ASH:<br />Ibritumomab Provides Benefit in Patients with Follicular Lymphoma
Anton Hagenbeek ANTON HAGENBEEK, University Medical Centre Utrecht For patients with advanced-stage follicular non-Hodgkin’s lymphoma, ibritumomab tiuxetan seems to prolong progression free surv

Live Report from ASH:<br />Can Intensive Immunochemotherapy Cure Mantle Cell Lymphoma?
Christian Geisler CHRISTIAN GEISLER, Rigshospitalet, Copenhagen Mantle cell lymphoma, which was previously considered incurable, has apparently been cured in some patients on a phase II study. Derek T

Live Report from ASH:<br />Oblimersen Extends Survival in Chronic Lymphocytic Leukemia
Susan O’Brien SUSAN O’BRIEN, MD Anderson Cancer Center, Houston For patients with relapsed or refractory CLL, oblimersen extends survival when added to standard fludarabine/cyclophosphamid

Live Report from ASH:<br />Dasatinib Effective At Two Years’ Follow Up in Chronic Phase CML
Richard Stone RICHARD STONE, Dana-Farber Cancer Institute, Boston GEORGE CANELLOS, Dana-Farber Cancer Institute New data shows that dasatinib is giving durable responses in patients with chronic phase

Live Report from ASH: Azacitidine ‘New Standard’ In High Risk Myelodysplastic Syndromes
Pierre Fenaux PIERRE FENAUX, Paris 13 University Results from a phase III study presented at ASH suggest that the hypomethylating agent azacitidine should be the new standard of care for patients with

Live Report from ASH:<br />Interleukin-2 For Acute Myeloid Leukemia In First Remission?
Jonathan Kolitz JONATHAN KOLITZ, Monter Cancer Center, Lake Success, NY GEORGE CANELLOS, Dana-Farber Cancer Institute For patients with acute myeloid leukemia in first remission, new data suggests tha

New Drug AMG 531 Effective in Splenectomized Patients with Chronic Immune Thrombocytopenic Purpura
Terry Gernsheimer TERRY GERNSHEIMER, University of Washington Medical Center, Seattle An investigational drug AMG 531 has increased and sustained platelet counts in splenectomized patients with chroni

Large Risk Reduction For Rivaroxaban In Blood Clot Prevention
Bengt Eriksson REFERENCE: Abstract 6, American Society of Hematology Annual Meeting, December 8-11 2007, Atlanta BENGT ERIKSSON, Gothenburg University In a large phase III trial of patients having a h

Two New Second-Line Options For Patients With Advanced or Metastatic Non-Small Cell Lung Cancer
Jean-Yves Douillard Gordon McVie REFERENCE: Abstracts: 6507 & 2LB, ECCO 14, The European Cancer Conference, Barcelona, 23 – 27 September 2007 JEAN-YVES DOUILLARD, Centre René Gauducheau, N

Rosuvastatin: No Significant Benefit for Older Patients with Systolic Heart Failure: CORONA Study Results
Ake Hjalmarson Gordon Tomaselli REFERENCE: Late Breaking Clinical Trials, Session 2, American Heart Association Scientific Sessions, 4-7 November, 2007, Orlando, Florida N Engl J Med 2007;357 AKE HJAL

TRITON-TIMI 38 Prasugrel Or Clopidogrel In Percutaneous Intevention?
Gordon Tomaselli Daniel Jones REFERENCE: Late Breaking Clinical Trials 1, American Heart Association Scientific Sessions, 4-7 November, 2007, Orlando, Florida GORDON TOMASELLI, Johns Hopkins Universit

Long Term Outcomes of Drug Eluting and Bare Metal Stents in Patients Undergoing PCI
Laura Mauri Raymond Gibbons REFERENCE: Late Breaking Special Session, American Heart Association Scientific Sessions, 4-7 November, 2007, Orlando, Florida LAURA MAURI, Brigham and Woman’s Hospit

Stable Angina: Add PCI To Medical Therapy If Guided by SPECT-Detected Ischemia? COURAGE Nuclear Sub-Study Results
REFERENCE: Abstract: Late Breaking Clinical Trials, Session 1, American Heart Association Scientific Sessions, 4-7 November, 2007, Orlando, Florida LESLEE SHAW, Emory University, Atlanta COMMENT: DANI

Neoadjuvant Trastuzumab: Marked Benefit in HER2-Positive Inflammatory Breast Cancer
Jose Baselga Gordon McVie REFERENCE: ABSTRACT 2030, ECCO 14, The European Cancer Conference, Barcelona, 23 – 27 September 2007 JOSE BASELGA, Vall d’Hebron University Hospital, Barcelona CO

DUET 1 and 2 Trials: TMC 125 has Superior Virologic and Immunologic Response Rates
Pedro Cahn REFERENCE: Abstract H-717, 47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 PEDRO CAHN, Juan A. Fernández Hospital, Buenos Aires Etraviri

Chronic Stable Angina: Should ESC Guidelines on Clopidogrel as Pre-Treatment to Planned Coronary Angiography be Changed?

London School of Hygiene & Tropical Medicine Audio News Review, August 31st, 2007

KRAS Mutation: Powerful Molecular Predictor of Cetuximab Response in Patients With Metastatic Colorectal Cancer
Pierre Laurent-Puig Bill Hait REFERENCE: ABSTRACT: 5671, American Association for Cancer Research, April 14-18, 2007, Los Angeles PIERRE LAURENT-PUIG, Hôpital Européen Georges Pompidou, Paris COMMEN

Virus Plus Cytokine Fight Primary and Metastatic Cancer
Paul Fisher REFERENCE: Meet the Professor Session, AACR 2007, Los Angeles PAUL FISHER, Columbia University, New York Patients with cancer could soon be treated with adenoviruses capable of infecting b

Statins Protect Heart Patients from Sepsis
Donald Redelmeier, University of Toronto Abstract: Lancet 2006; 367:413 Treatment with the lipid lowering agents statins reduced the incidence of sepsis among a large group of patients with cardiovasc

Clostridium difficile: Back in Hospitals and Meaning Business
Lance Peterson Lance Peterson, Evanston Northwestern Healthcare, Illinois The bacterium clostridium difficile that can cause diarrhoea in hospital patients is making a resurgence. It’s potential

Community-Associated MRSA: Public Housing, Jail: Risks?
Bala Hota Bala Hota, Cook County Hospital, Chicago Researchers are now seeing growing numbers of MRSA infections in the community as well as in hospitals. One study presented at ICAAC was looking at p

Rituximab Maintenance after Chemotherapy Gives Better Outcomes in Advanced Follicular Lymphoma
Sandra Horning Abstract 349 Sandra Horning, Stanford University Medical Center It is not necessary to use rituximab along with standard CVP (cyclophosphamide, vincristine, predinsone) induction therap

Non-Anthracyline Regimen May Be O.K. for Patients with Early Breast Cancer taking Trastuzumab (Herceptin)
Dennis Slamon, UCLA School of Medicine, Los Angeles It may be reasonable to replace the anthracycline component of adjuvant chemotherapy with carboplatin in HER-2 positive patients with early breast c

Eicosapentaenoic Acid: Prevention of Coronary Artery Disease
A 20 000-person study of eicosapentaenoic acid supplements gave solid scientific support for EPA use to prevent cardiovascular events among patients with established coronary artery disease. Mitsuhiro

Diabetic Patients: Some Benefits from Fibrates
Anthony Keech Among nearly 10 000 patients with maturity onset diabetes the use of fenofibrate to lower cholesterol produced a 24 per cent statistically significant reduction of cardiovascular events,

Europe Leaps to Action on Heart-Unfriendly Lifestyles
David Wood Heart disease patients need to change lifestyle and not just take medicines. That’s the message in Stockholm from the EuroAction Project, which is investigating the potential of a nur

Fondaparinux: Better than Enoxaparin for Patients with Acute Coronary Syndromes?
Freek Verheugt Shamir Mehta of McMaster University told Audio Medica in Stockholm about the OASIS-5/MICHELANGELO results comparing the new anti-thrombotic therapy, fondaparinux, with enoxaparin among