inhibitor
Interviews and expert commentary tagged “inhibitor” — the latest oncology research and clinical practice from the Audio Journal of Oncology.

Audio Journal of Oncology Volume 16 Number 9
Scientific Editors: George Canellos (Boston), Pat Price (Manchester), Gianni Bonadonna (Milan), Gordon McVie (Milan) Commenting Expert: Emiel Rutgers, Netherlands Cancer Institute, Amsterdam Angel Rod

New Targets Bring Promise For Lung Cancer Therapy
Egbert Smit EGBERT SMIT, Free University of Amsterdam There are a number of promising new molecular targets for lung cancer chemotherapy which were discussed at the Turin congress by Egbert Smit. He t

Target Angiogenesis for Lung Cancer With Multiple Tyrosine Kinase Inhibitors
Silvia Novello SILVIA NOVELLO, University of Turin Future improvements in drug treatment of lung cancer may be made by inhibiting more than one tyrosine kinase simultaneously. So said Silvia Novello w

Oral Capecitabine: As Good As Fluorouracil Second Line for Metastatic Colorectal Cancer
David Cunningham REFERENCE: Abstract 3012, ECCO 14, The European Cancer Conference, Barcelona, 23 – 27 September 2007 DAVID CUNNINGHAM, Royal Marsden Hospital, London The oral agent capeticabine

ATAC Trial: Anastrozole Still Superior At Over Eight Years’ Follow Up
Jack Cuzick JACK CUZICK, Wolfson Institute of Preventive Medicine, London New data from the ATAC trial, which is testing anastrozole and tamoxifen in early breast cancer, have demonstrated the continu

Eptifibatide After PCI: Brief Infusion Is Just As Good
Anthony Fung REFERENCE: Late Breaking Clinical Trials Session I, American Heart Association Scientific Sessions, 4-7 November, 2007, Orlando, Florida ANTHONY FUNG, University of British Columbia, Vanc

Bortezomib for Multiple Myeloma Can Cause Reactivation of Viruses
Georg Härter REFERENCE:47th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, 2007 GEORG HÄRTER, University Hospital, Ulm For patients with multiple myeloma b

KRAS Mutation: Powerful Molecular Predictor of Cetuximab Response in Patients With Metastatic Colorectal Cancer
Pierre Laurent-Puig Bill Hait REFERENCE: ABSTRACT: 5671, American Association for Cancer Research, April 14-18, 2007, Los Angeles PIERRE LAURENT-PUIG, Hôpital Européen Georges Pompidou, Paris COMMEN

Virus Plus Cytokine Fight Primary and Metastatic Cancer
Paul Fisher REFERENCE: Meet the Professor Session, AACR 2007, Los Angeles PAUL FISHER, Columbia University, New York Patients with cancer could soon be treated with adenoviruses capable of infecting b

Direct Renin Inhibitor Combined with Angiotensin Receptor Blockade Gives Additional Blood Pressure Lowering
SUZANNE OPARIL, University of Alabama, Birmingham REFERENCE: Abstract 405-12, American College of Cardiolgy New Orleans A combination of two antihypertensive agents has given improved blood pressure c

Integrase Inhibitor Raltegravir Doubles Antiviral Response Rate in Treatment Experienced HIV-Infected Patients Compared to Optimised Background Therapy Alone
ROY STEIGBIGEL, State University of New York at Stony Brook JOHN W. MELLORS, University of Pittsburgh REFERENCE: Abstract 105aLB, 105bLB, 14th Conference on Retroviruses and Opportunistic Infections,

ASCO Audio Journal of Oncology in Advance – February 1st, 2007 – reporting from American Society of Hematology 48th Annual Meeting, December 9-12, 2006 Orlando
Francis Giles Ken Kaushansky Heather Leitch Nancy Berliner Corrado Tarella Vincent Rajkumar Robert Kyle Aurora Kinase BCR-ABL Inhibitor Beats T315-I Mutation in Patients with Chronic Myeloid Leukemia

Audio Journal of Cardiovascular Medicine: reporting from American Heart Association Scientific Sessions, Chicago, November 12-15, 2006
Joseph Muhlestein Sidney Smith Joost Daemen Drug Eluting Stents: More Deaths in Real World Use REFERENCE: American Heart Association Scientific Sessions, Chicago, November 12-15, 2006. Abstract: 2225

Audio Journal of Cardiovascular Medicine: reporting from American Heart Association Scientific Sessions, Chicago, November 12-15, 2006
Theodore Mazzone Timothy Gardner Christopher Cannon Atherosclerosis Halted in Type 2 Diabetes by Pioglitazone for Glycemic Control REFERENCE: American Heart Association Scientific Sessions, Chicago, N

ASCO Audio Journal of Oncology – June 15th 2006
Arlene Forastiere Everett Vokes Michael Skinner Mark Chambers Larynx Cancer: Concurrent Chemoradiotherapy: Best for Larynx Preservation REFERENCE: Abstract 5517 Arlene Forastiere, Sidney Kimmel Compre

New Protease Inhibitor for HIV Patients with Few Options
Timothy Wilkin Timothy Wilkin, Weill Cornell Medical College, New York A protease inhibitor, currently known as TMC114 has been tested in the POWER II study among some 300 patients who had failed mult

Statins and ARBs: a Special Combination?
John McMurray The VALIANT trial compared ACE-inhibitor, ARB and a combination of the two in high-risk post-MI patients, and found there may be an interaction between them and statins. John McMurray fr

50% of Women are Over-treated in Acute Coronary Syndromes
Registry analysis suggests women often receive too much treatment with glycoprotein 2B3A inhibitors. Duke University’s Karen Alexander told us more. [audio:https://www.audiomedica.com/podcasting

NSAIDs Raise Death Risk post-MI
Gunnar Gislason As the dust continues to settle on the Vioxx issue, there is naturally a desire to look further at potential cardiovascular risks associated with COX-2 inhibitors and, indeed, other no

PREAMI: Perindopril Improves Remodelling in Older Patients with Acute Myocardial Infarction
Audio Medica talked with Roberto Ferrari , Vice President of the ESC, about the PREAMI study on the use of the ACE inhibitor perindopril in older patients who have survived acute myocardial infarction

CIBIS-3 Study: ACE Inhibitor before Beta Blocker for Congestive Heart Failure?
Ronnie Willenheimer It could be just as good to start treatment for heart failure with a beta blocker first and subsequently use an ACE inhibitor, as the more convetional use of an ACE inhibitor first