Philip Barter Gordon Tomaselli REFERENCE: Late Breaking Clinical Trials, Session 2, American Heart Association Scientific Sessions, 4-7 November, 2007, Orlando, Florida N Engl J Med 2007;357 PHILIP BA
Philip Barter
Gordon Tomaselli
REFERENCE: Late Breaking Clinical Trials, Session 2, American Heart Association Scientific Sessions, 4-7 November, 2007, Orlando, FloridaN Engl J Med 2007;357PHILIP BARTER, Heart Research Institute, Sydney, AustraliaCOMMENT: GORDON TOMASELLI, Johns Hopkins University, BaltimoreA randomized double-blind study involving over 15,000 patients at high cardiovascular risk which looked at the new agent torcetrapib (an inhibitor of cholesteryl ester transfer protein, CETP) resulted in higher mortality in the experimental arm. The study compared torcetrapib plus atorvastatin with atorvatstin alone. Inhibition of CETP increases HDL levels and reduces LDL levels and should combat atherosclerosis. Sarah Maxwell spoke withPhilip Barterwho presented data on the ILLUMINATE trial at the American Heart Association meeting in Orlando.
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